Myeloid ABCG1 Deficiency Enhances Apoptosis and Initiates Efferocytosis in Bronchoalveolar Lavage Cells of Murine Multi-Walled Carbon Nanotube-Induced Granuloma Model

Myeloid ABCG1 Deficiency Enhances Apoptosis and Initiates Efferocytosis in Bronchoalveolar Lavage Cells of Murine Multi-Walled Carbon Nanotube-Induced Granuloma Model

The use of carbon nanotubes has increased in the past few decades. Carbon nanotubes are implicated in the pathogenesis of pulmonary sarcoidosis, a chronic granulomatous inflammatory condition. We developed a murine model of chronic granulomatous inflammation using multiwall carbon nanotubes (MWCNT)...

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Bibliographic Details
Main Authors: Eman Soliman, Sophia Bhalla, Ahmed E. M. Elhassanny, Anagha Malur, David Ogburn, Nancy Leffler, Achut G. Malur, Mary Jane Thomassen
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
carbon nanotubes
lipid transporter ABCG1
efferocytosis
apoptosis
granuloma-associated lung fibrosis
Online Access:https://www.mdpi.com/1422-0067/23/1/47

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https://www.mdpi.com/1422-0067/23/1/47

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