Graft-versus-Leukemia Effect Following Hematopoietic Stem Cell Transplantation for Leukemia

Graft-versus-Leukemia Effect Following Hematopoietic Stem Cell Transplantation for Leukemia

The success of hematopoietic stem cell transplantation (HSCT) lies with the ability of the engrafting immune system to remove residual leukemia cells via a graft-versus-leukemia effect (GvL), caused either spontaneously post-HSCT or via donor lymphocyte infusion. GvL effects can also be initiated by...

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Bibliographic Details
Main Authors: Anne M. Dickinson, Jean Norden, Shuang Li, Ilona Hromadnikova, Christoph Schmid, Helga Schmetzer, Hans Jochem-Kolb
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Immunology
Subjects:
graft-versus-leukemia effect
animal models
donor lymphocyte infusion
allogenic natural killer cells
leukaemia associated antigens (LAA)
LAA specific T cells
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00496/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00496/full

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