DNA damage response(DDR): a link between cellular senescence and human cytomegalovirus

Abstract The DNA damage response (DDR) is a signaling cascade that is triggered by DNA damage, involving the halting of cell cycle progression and repair. It is a key event leading to senescence, which is characterized by irreversible cell cycle arrest and the senescence-associated secretory phenoty...

Full description

Bibliographic Details
Main Authors: Xinna Wu, Xuqiang Zhou, Sanying Wang, Genxiang Mao
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-023-02203-y