Defective Viral Particles Produced in Mast Cells Can Effectively Fight Against Lethal Influenza A Virus

Defective Viral Particles Produced in Mast Cells Can Effectively Fight Against Lethal Influenza A Virus

Mast cells play an important role in the pathogenesis of highly pathogenic H5N1 avian influenza virus (H5N1-HPAIV) infection. Defective viral particles (DPs) can interfere with the replication of infectious viruses and stimulate the innate immune response of host cells. However, DPs arising from mas...

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Bibliographic Details
Main Authors: Caiyun Huo, Jinlong Cheng, Jin Xiao, Mingyong Chen, Shumei Zou, Haiyan Tian, Ming Wang, Lunquan Sun, Zhihui Hao, Yanxin Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Microbiology
Subjects:
highly pathogenic H5N1 avian influenza virus
mast cells
defective viral particles
therapeutic protection
interferon signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.553274/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.553274/full

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