High-throughput nephelometry methodology for qualitative determination of aqueous solubility of chemical libraries

The purpose of the protocol reported in this work is the solubility profiling of large chemical libraries using nephelometry. This technique allows the qualitative classification of compounds as highly, moderately, or poorly water-soluble. The described methodology is not intended to yield quantitat...

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Bibliographic Details
Main Authors: Jose Brea, Maria J. Varela, Geert A. Daudey, Maria I. Loza
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:SLAS Discovery
Online Access:http://www.sciencedirect.com/science/article/pii/S247255522400011X