Numerical modelling of the dissolution of drug nanocrystals and its application to industrial product development
The apparent solubility of drug nanocrystals in equilibrium was experimentally determined for a drug-stabilizer system with different particle size distributions. True supersaturation was identified for ultrafine drug nanocrystals with an almost 2-fold increase compared to the thermodynamic solubil...
| Autori principali: | , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
International Association of Physical Chemists (IAPC)
2022-08-01
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| Serie: | ADMET and DMPK |
| Accesso online: | https://pub.iapchem.org/ojs/index.php/admet/article/view/1437 |