Genetic variants in EPAS1 contribute to adaptation to high-altitude hypoxia in Sherpas.

Sherpas comprise a population of Tibetan ancestry in the Himalayan region that is renowned for its mountaineering prowess. The very small amount of available genetic information for Sherpas is insufficient to explain their physiological ability to adapt to high-altitude hypoxia. Recent genetic evide...

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Bibliographic Details
Main Authors: Masayuki Hanaoka, Yunden Droma, Buddha Basnyat, Michiko Ito, Nobumitsu Kobayashi, Yoshihiko Katsuyama, Keishi Kubo, Masao Ota
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3515610?pdf=render