Single‐cell transcriptome analysis reveals functional changes in tumour‐infiltrating B lymphocytes after chemotherapy in oesophageal squamous cell carcinoma

Single‐cell transcriptome analysis reveals functional changes in tumour‐infiltrating B lymphocytes after chemotherapy in oesophageal squamous cell carcinoma

Abstract Background Tumour immune microenvironment is related with carcinogenesis and efficacy of immunotherapy. B cells play major roles in humoral immunity, but detailed functions of tumour‐infiltrating B lymphocytes (TIL‐Bs) are unknown. Therefore, our aim was to investigate the functional hetero...

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Bibliographic Details
Main Authors: Shoichi Nakamura, Kenoki Ohuchida, Yoshiki Ohtsubo, Yutaka Yamada, Chikanori Tsutsumi, Sho Okuda, Kyoko Hisano, Yuki Mochida, Tomohiko Shinkawa, Chika Iwamoto, Nobuhiro Torata, Yusuke Mizuuchi, Koji Shindo, Kohei Nakata, Taiki Moriyama, Takehiro Torisu, Eishi Nagai, Takashi Morisaki, Takanari Kitazono, Yoshinao Oda, Masafumi Nakamura
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Clinical and Translational Medicine
Subjects:
oesophageal squamous cell carcinoma
neoadjuvant chemotherapy
single‐cell transcriptome
tumour immune microenvironment
tumour infiltrating B lymphocytes
Online Access:https://doi.org/10.1002/ctm2.1181

Internet

https://doi.org/10.1002/ctm2.1181

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