Model for the Controlled Synthesis of O-Antigen Repeat Units Involving the WaaL Ligase
ABSTRACT The Wzx/Wzy O-antigen pathway involves synthesis of a repeat unit (O unit) consisting of 3 to 8 sugars on an inner-membrane-embedded lipid carrier. These O units are translocated across the membrane to its periplasmic face by Wzx, while retaining linkage to the carrier, and then polymerized...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2016-02-01
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| Series: | mSphere |
| Online Access: | https://journals.asm.org/doi/10.1128/mSphere.00074-15 |