RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases.

Mitochondrial translation defects can be due to mutations affecting mitochondrial- or nuclear-encoded components. The number of known nuclear genes involved in mitochondrial translation has significantly increased in the past years. RCC1L (WBSCR16), a putative GDP/GTP exchange factor, has recently b...

Full description

Bibliographic Details
Main Authors: Aurelio Reyes, Paola Favia, Sara Vidoni, Vittoria Petruzzella, Massimo Zeviani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008923