Potential role of lipophagy impairment for anticancer effects of glycolysis-suppressed pancreatic ductal adenocarcinoma cells

Potential role of lipophagy impairment for anticancer effects of glycolysis-suppressed pancreatic ductal adenocarcinoma cells

Abstract Although increased aerobic glycolysis is common in various cancers, pancreatic ductal adenocarcinoma (PDAC) cells can survive a state of glycolysis suppression. We aimed to identify potential therapeutic targets in glycolysis-suppressed PDAC cells. By screening anticancer metabolic compound...

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Bibliographic Details
Main Authors: Zhiheng Zhang, Haruna Aoki, Keitaro Umezawa, Joshua Kranrod, Natsumi Miyazaki, Taichi Oshima, Takuya Hirao, Yuri Miura, John Seubert, Kousei Ito, Shigeki Aoki
Format: Article
Language:English
Published: Nature Publishing Group 2024-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01933-4

Internet

https://doi.org/10.1038/s41420-024-01933-4

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