Liquid–Liquid Phase Separation in the Presence of Macromolecular Crowding and State-dependent Kinetics

Liquid–Liquid Phase Separation in the Presence of Macromolecular Crowding and State-dependent Kinetics

Biomolecular condensates formed via liquid–liquid phase separation (LLPS) are increasingly being shown to play major roles in cellular self-organization dynamics in health and disease. It is well established that macromolecular crowding has a profound impact on protein interactions, particularly tho...

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Bibliographic Details
Main Authors: Alick-O. Vweza, Chul-Gyu Song, Kil-To Chong
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
biomolecular condensates
macromolecular crowding
membraneless organelles
liquid–liquid phase separation
intrinsically disordered proteins
state-dependent reactions
Online Access:https://www.mdpi.com/1422-0067/22/13/6675

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https://www.mdpi.com/1422-0067/22/13/6675

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