Influence of letermovir treatment on gut inflammation in people living with HIV on antiretroviral therapy: protocol of the open-label controlled randomised CIAO study

Influence of letermovir treatment on gut inflammation in people living with HIV on antiretroviral therapy: protocol of the open-label controlled randomised CIAO study

Introduction Chronic cytomegalovirus (CMV) infection is very frequent in people living with HIV (PLWH). High anti-CMV IgG titres, which may be linked to transient CMV replication, have been associated with earlier mortality, CD8 T-cell expansion, lower CD4/CD8 ratio and increased T-cell senescence....

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Bibliographic Details
Main Authors: Jean-Pierre Routy, Bertrand Lebouché, Nicolas Chomont, Stéphane Isnard, Réjean Thomas, Talat Bessissow, Guy Boivin, Alexandra de Pokomandy, Nadine Kronfli, Marina Klein, Cécile Tremblay, Léna Royston, Simeng Bu, Carolina A. Berini, Peter L. Lakatos, Cecilia T. Costiniuk
Format: Article
Language:English
Published: BMJ Publishing Group 2023-01-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/1/e067640.full

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https://bmjopen.bmj.com/content/13/1/e067640.full

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