<sup>64</sup>Cu<sup>2+</sup> Complexes of Tripodal Amine Ligands’ In Vivo Tumor and Liver Uptakes and Intracellular Cu Distribution in the Extrahepatic Bile Duct Carcinoma Cell Line TFK-1: A Basic Comparative Study

<sup>64</sup>Cu<sup>2+</sup> Complexes of Tripodal Amine Ligands’ In Vivo Tumor and Liver Uptakes and Intracellular Cu Distribution in the Extrahepatic Bile Duct Carcinoma Cell Line TFK-1: A Basic Comparative Study

Copper (Cu) is a critical element for cancer cell proliferation and considerably accumulates in the nucleus. <sup>64</sup>Cu<sup>2+</sup> is an anticancer radiopharmaceutical that targets the copper requirement of cancer cells. However, intravenously injected <sup>64<...

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Bibliographic Details
Main Authors: Mitsuhiro Shinada, Masashi Takahashi, Chika Igarashi, Hiroki Matsumoto, Fukiko Hihara, Tomoko Tachibana, Masakazu Oikawa, Hisashi Suzuki, Ming-Rong Zhang, Tatsuya Higashi, Hiroaki Kurihara, Yukie Yoshii, Yoshihiro Doi
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Pharmaceuticals
Subjects:
copper requirement
cancer
PIXE
tripodal amine ligands
<sup>64</sup>Cu<sup>2+</sup> ions
<sup>64</sup>Cu<sup>2+</sup> complexes
Online Access:https://www.mdpi.com/1424-8247/17/7/820

Internet

https://www.mdpi.com/1424-8247/17/7/820

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