Interleukin-4 Supports the Suppressive Immune Responses Elicited by Regulatory T Cells

Interleukin-4 Supports the Suppressive Immune Responses Elicited by Regulatory T Cells

Interleukin-4 (IL-4) has been considered as one of the tolerogenic cytokines in many autoimmune animal models and clinical settings. Despite its role in antagonizing pathogenic Th1 responses, little is known about whether IL-4 possesses functions that affect regulatory T cells (Tregs). Tregs are spe...

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Bibliographic Details
Main Authors: Wei-Cheng Yang, Yih-Shiou Hwang, Ying-Yu Chen, Chao-Lin Liu, Chia-Ning Shen, Wei-Hsin Hong, Sheng-Min Lo, Chia-Rui Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
regulatory T cell
interleukin-4
granzyme
immunosuppression
cell survival
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01508/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01508/full

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