Host-directed therapy in foals can enhance functional innate immunity and reduce severity of Rhodococcus equi pneumonia

Abstract Pneumonia caused by the intracellular bacterium Rhodococcus equi is an important cause of disease and death in immunocompromised hosts, especially foals. Antibiotics are the standard of care for treating R. equi pneumonia in foals, and adjunctive therapies are needed. We tested whether nebu...

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Bibliographic Details
Main Authors: Angela I. Bordin, Noah D. Cohen, Steve Giguère, Jocelyne M. Bray, Londa J. Berghaus, Brenton Scott, Rena Johnson, Magnus Hook
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82049-y