Increased glycolysis and cellular crosstalk in eosinophilic chronic rhinosinusitis with nasal polyps

Increased glycolysis and cellular crosstalk in eosinophilic chronic rhinosinusitis with nasal polyps

IntroductionChronic rhinosinusitis (CRS) is a chronic inflammatory disease of the sinonasal mucosa with distinct endotypes including type 2 (T2) high eosinophilic CRS with nasal polyps (eCRSwNP), T2 low non-eosinophilic CRS with nasal polyps (neCRSwNP), and CRS without nasal polyps (CRSsNP).MethodsG...

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Bibliographic Details
Main Authors: George X. Huang, Michael V. Mandanas, Sarah Djeddi, Daniela Fernandez-Salinas, Maria Gutierrez-Arcelus, Nora A. Barrett
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
chronic rhinosinusitis
single cell RNA sequencing
epithelium
glycolysis
epithelial mesenchymal interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1321560/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1321560/full

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