Pedunculopontine Nucleus Dysconnectivity Correlates With Gait Impairment in Parkinson’s Disease: An Exploratory Study

Pedunculopontine Nucleus Dysconnectivity Correlates With Gait Impairment in Parkinson’s Disease: An Exploratory Study

BackgroundGait impairment is a debilitating and progressive feature of Parkinson’s disease (PD). Increasing evidence suggests that gait control is partly mediated by cholinergic signaling from the pedunculopontine nucleus (PPN).ObjectiveWe investigated whether PPN structural connectivity correlated...

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Bibliographic Details
Main Authors: Stephen Joza, Richard Camicioli, W. R. Wayne Martin, Marguerite Wieler, Myrlene Gee, Fang Ba
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson’s disease
pedunculopontine nucleus
gait impairments
MRI
diffusion tensor imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.874692/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.874692/full

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