Pyruvate carboxylase promotes malignant transformation of papillary thyroid carcinoma and reduces iodine uptake
Abstract Previous studies have shown that pyruvate carboxylase (PC) plays a key role in the occurrence and progression of thyroid cancer (TC); however, the relationship between PC and iodine-refractory TC is unclear. Therefore, the present study aimed to investigate the molecular mechanism of PC in...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-10-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-022-01214-y |