The Oligostilbene Gnetin H Is a Novel Glycolysis Inhibitor That Regulates Thioredoxin Interacting Protein Expression and Synergizes with OXPHOS Inhibitor in Cancer Cells

The Oligostilbene Gnetin H Is a Novel Glycolysis Inhibitor That Regulates Thioredoxin Interacting Protein Expression and Synergizes with OXPHOS Inhibitor in Cancer Cells

Since aerobic glycolysis was first observed in tumors almost a century ago by Otto Warburg, the field of cancer cell metabolism has sparked the interest of scientists around the world as it might offer new avenues of treatment for malignant cells. Our current study claims the discovery of gnetin H (...

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Bibliographic Details
Main Authors: Shivendra Singh, Flavia De Carlo, Mohamed A. Ibrahim, Patrice Penfornis, Alan J. Mouton, Siddharth K. Tripathi, Ameeta K. Agarwal, Linda Eastham, David S. Pasco, Premalatha Balachandran, Pier Paolo Claudio
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
glycolysis
gnetin H
natural products
oligostilbene
Warburg effect
Online Access:https://www.mdpi.com/1422-0067/24/9/7741

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https://www.mdpi.com/1422-0067/24/9/7741

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