Alterations in brain-derived neurotrophic factor in the mouse hippocampus following acute but not repeated benzodiazepine treatment.

Benzodiazepines (BZs) are safe drugs for treating anxiety, sleep, and seizure disorders, but their use also results in unwanted effects including memory impairment, abuse, and dependence. The present study aimed to reveal the molecular mechanisms that may contribute to the effects of BZs in the hipp...

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Bibliographic Details
Main Authors: Stephanie C Licata, Nina M Shinday, Megan N Huizenga, Shayna B Darnell, Gavin R Sangrey, Uwe Rudolph, James K Rowlett, Ghazaleh Sadri-Vakili
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3868703?pdf=render