Factor XII – What's important but not commonly thought about
Abstract Factor XII (FXII) becomes a serine protease when blood is exposed to artificial medical surfaces or when pathologic surfaces arise in disease states leading to its autoactivation. Initiation of the blood coagulation cascade was the first recognized activity of FXIIa. Blocking FXIIa activity...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-10-01
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Series: | Research and Practice in Thrombosis and Haemostasis |
Subjects: | |
Online Access: | https://doi.org/10.1002/rth2.12235 |