Interaction between NSMCE4A and GPS1 links the SMC5/6 complex to the COP9 signalosome

Interaction between NSMCE4A and GPS1 links the SMC5/6 complex to the COP9 signalosome

Abstract Background The SMC5/6 complex, cohesin and condensin are the three mammalian members of the structural maintenance of chromosomes (SMC) family, large ring-like protein complexes that are essential for genome maintenance. The SMC5/6 complex is the least characterized complex in mammals; howe...

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Bibliographic Details
Main Authors: András Horváth, Gergely Rona, Michele Pagano, Philip W. Jordan
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Molecular and Cell Biology
Subjects:
NSMCE4A
SMC5/6
GPS1
COP9 signalosome
DNA repair
Deneddylation
Online Access:http://link.springer.com/article/10.1186/s12860-020-00278-x

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http://link.springer.com/article/10.1186/s12860-020-00278-x

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