Appelmans protocol – A directed in vitro evolution enables induction and recombination of prophages with expanded host range

Appelmans protocol – A directed in vitro evolution enables induction and recombination of prophages with expanded host range

Infections caused by carbapenem-resistant Acinetobacter baumannii (CRAB) present significant healthcare challenges due to limited treatment options. Bacteriophage (phage) therapy offers potential as an alternative treatment. However, the high host specificity of phages poses challenges for their the...

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Bibliographic Details
Main Authors: Thao Nguyen Vu, Justin Ryan Clark, Eris Jang, Roshan D'Souza, Le Phuong Nguyen, Naina Adren Pinto, Seongjun Yoo, Ricardo Abadie, Anthony William Maresso, Dongeun Yong
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Virus Research
Subjects:
Bacteriophage
Acinetobacter baumannii
Phage therapy
Host range expansion
Appelmans protocol
Prophage induction
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170223002344

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http://www.sciencedirect.com/science/article/pii/S0168170223002344

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