Beyond Maternal Tolerance: Education of Uterine Natural Killer Cells by Maternal MHC Drives Fetal Growth

Reproductive immunology has moved on from the classical Medawar question of 60 years ago “why doesn’t the mother reject the fetus?”. Looking beyond fetal-maternal tolerance, modern reproductive immunology focuses on how the maternal immune system supports fetal growth. Maternal uterine natural kille...

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Bibliographic Details
Main Authors: Delphine M. Depierreux, Jens Kieckbusch, Norman Shreeve, Delia A. Hawkes, Bryan Marsh, Robert Blelloch, Andrew Sharkey, Francesco Colucci
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.808227/full