Reducing tumor invasiveness by ramucirumab and TGF‐β receptor kinase inhibitor in a diffuse‐type gastric cancer patient‐derived cell model

Reducing tumor invasiveness by ramucirumab and TGF‐β receptor kinase inhibitor in a diffuse‐type gastric cancer patient‐derived cell model

Abstract Background Diffuse‐type gastric cancer (GC) is known to be more aggressive and relatively resistant to conventional chemotherapy. Hence, more optimized treatment strategy is urgently needed in diffuse‐type GC. Methods Using a panel of 10 GC cell lines and 3 GC patient‐derived cells (PDCs),...

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Bibliographic Details
Main Authors: Song‐Yi Lee, Seonggyu Byeon, Jihoon Ko, Sujin Hyung, In‐Kyoung Lee, Noo Li Jeon, Jung Yong Hong, Seung Tae Kim, Se Hoon Park, Jeeyun Lee
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Cancer Medicine
Subjects:
angiogenesis
epithelial–mesenchymal transition (EMT)
gastric cancer
ramucirumab
Online Access:https://doi.org/10.1002/cam4.4259

Internet

https://doi.org/10.1002/cam4.4259

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