Transcriptional Trajectories in Mouse Limb Buds Reveal the Transition from Anterior-Posterior to Proximal-Distal Patterning at Early Limb Bud Stage

Limb patterning relies in large part on the function of the <i>Hox</i> family of developmental genes. While the differential expression of <i>Hox</i> genes shifts from the anterior–posterior (A–P) to the proximal–distal (P–D) axis around embryonic day 11 (E11), whether this s...

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Bibliographic Details
Main Authors: Ines Desanlis, Rachel Paul, Marie Kmita
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Journal of Developmental Biology
Subjects:
Online Access:https://www.mdpi.com/2221-3759/8/4/31