Tanshinone IIA Promotes Pulmonary Artery Smooth Muscle Cell Apoptosis in Vitro by Inhibiting the JAK2/STAT3 Signaling Pathway

Tanshinone IIA Promotes Pulmonary Artery Smooth Muscle Cell Apoptosis in Vitro by Inhibiting the JAK2/STAT3 Signaling Pathway

Background: Tanshinone IIA inhibits the proliferation of pulmonary artery smooth muscle cells (PASMCs), but the potential mechanisms of its effects on PASMCs apoptosis remain unclear. Methods: Rat were subjected to hypoxia for 9 days with or without Tanshinone IIA treatment. PASMCs were exposed to t...

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Bibliographic Details
Main Authors: Minggang Chen, Yumei Liu, Dan Yi, Liuping Wei, Yumei Li, Li Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Tanshinone IIA
PASMCs
JAK2/STAT3
Apoptosis
Cx43
Online Access:http://www.karger.com/Article/FullText/358682

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http://www.karger.com/Article/FullText/358682

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