A Dereplication and Bioguided Discovery Approach to Reveal New Compounds from a Marine-Derived Fungus Stilbella fimetaria

A Dereplication and Bioguided Discovery Approach to Reveal New Compounds from a Marine-Derived Fungus Stilbella fimetaria

A marine-derived Stilbella fimetaria fungal strain was screened for new bioactive compounds based on two different approaches: (i) bio-guided approach using cytotoxicity and antimicrobial bioassays; and (ii) dereplication based approach using liquid chromatography with both diode array detection and...

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Bibliographic Details
Main Authors: Sara Kildgaard, Karolina Subko, Emma Phillips, Violaine Goidts, Mercedes de la Cruz, Caridad Díaz, Charlotte H. Gotfredsen, Birgitte Andersen, Jens C. Frisvad, Kristian F. Nielsen, Thomas O. Larsen
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Marine Drugs
Subjects:
bioguided-discovery
dereplication
cytotoxicity
antifungal
MS/HRMS
marine-derived
pimarane-type diterpenoids
ilicicolin H
Online Access:https://www.mdpi.com/1660-3397/15/8/253

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https://www.mdpi.com/1660-3397/15/8/253

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