Current status and future perspectives of HLA-edited induced pluripotent stem cells
Abstract In 2007, Human-induced pluripotent stem cells (iPSCs) were generated by transducing four genes (Oct3/4, Sox2, Klf4, c-Myc). Because iPSCs can differentiate into any types of cells in the body and have fewer ethical issues compared to embryonic stem (ES) cells, application of iPSCs for regen...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-10-01
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Series: | Inflammation and Regeneration |
Online Access: | http://link.springer.com/article/10.1186/s41232-020-00132-9 |