Tartrate resistant acid phosphatase 5 (TRAP5) mediates immune cell recruitment in a murine model of pulmonary bacterial infection

Tartrate resistant acid phosphatase 5 (TRAP5) mediates immune cell recruitment in a murine model of pulmonary bacterial infection

IntroductionDuring airway infection, upregulation of proinflammatory cytokines and subsequent immune cell recruitment is essential to mitigate bacterial infection. Conversely, during prolonged and non-resolving airway inflammation, neutrophils contribute to tissue damage and remodeling. This occurs...

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Bibliographic Details
Main Authors: Lloyd Tanner, Jesper Bergwik, Ravi K. V. Bhongir, Manoj Puthia, Pernilla Lång, Mohamad N. Ali, Charlotte Welinder, Patrik Önnerfjord, Jonas S. Erjefält, Lena Palmberg, Göran Andersson, Arne Egesten
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
NF-κB
immune cell recruitment
Pseudomonas aeruginosa
cystic fibrosis
TRAP5/ACP5
SPP1/OPN
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1079775/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1079775/full

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