The causal relationship between metabolic factors, drinking, smoking and intrahepatic cholangiocarcinoma: a Mendelian randomization study

The causal relationship between metabolic factors, drinking, smoking and intrahepatic cholangiocarcinoma: a Mendelian randomization study

BackgroundIntrahepatic cholangiocarcinoma (iCCA) is the second most common primary liver cancer. While multiple risk factors for iCCA have been established, metabolic diseases (obesity, diabetes, NAFLD, dyslipidemia, and hypertension) and other risk factors, including smoking and drinking, are still...

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Bibliographic Details
Main Authors: Shan-shan Qin, Guo-qiang Pan, Qun-bo Meng, Jin-bo Liu, Zi-yu Tian, Shou-jing Luan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
Mendelian randomization
controversial risk factors
ICCA
causal relationship
GWAS data
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1203685/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1203685/full

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