The rate of spontaneous mutations in yeast deficient for MutSβ function

AbstractMutations in simple sequence repeat loci underlie many inherited disorders in humans, and are increasingly recognized as important determinants of natural phenotypic variation. In eukaryotes, mutations in these sequences are primarily repaired by the MutSβ mismatch repair com...

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Bibliographic Details
Main Authors: Yevgeniy Plavskin, Maria Stella de Biase, Roland F Schwarz, Mark L Siegal
Format: Article
Language:English
Published: Oxford University Press 2022-12-01
Series:G3: Genes, Genomes, Genetics
Online Access:https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkac330