A Single Point Mutation in the Mumps V Protein Alters Targeting of the Cellular STAT Pathways Resulting in Virus Attenuation

Mumps virus (MuV) is a neurotropic non-segmented, negative-stranded, enveloped RNA virus in the <i>Paramyxovirus</i> family. The 15.4 kb genome encodes seven genes, including the V/P, which encodes, among other proteins, the V protein. The MuV V protein has been shown to target the cellu...

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Bibliographic Details
Main Authors: Tahir Malik, Laurie Ngo, Trent Bosma, Steven Rubin
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/11/11/1016