Efficacy and safety of monotherapy and combination therapy of immune checkpoint inhibitors as first-line treatment for unresectable hepatocellular carcinoma: a systematic review, meta-analysis and network meta-analysis

Abstract Background Hepatocellular carcinoma (HCC) is one of the cancers with the highest morbidity and mortality. Sorafenib used to be the main treatment for unresectable HCC patients. However, regimens based on immune checkpoint inhibitors (ICIs) have attracted attention in recent years because of...

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Bibliographic Details
Main Authors: Qing Lei, Xin Yan, Huimin Zou, Yixuan Jiang, Yunfeng Lai, Carolina Oi Lam Ung, Hao Hu
Format: Article
Language:English
Published: Springer 2022-09-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-022-00559-1