Efficacy and safety of monotherapy and combination therapy of immune checkpoint inhibitors as first-line treatment for unresectable hepatocellular carcinoma: a systematic review, meta-analysis and network meta-analysis
Abstract Background Hepatocellular carcinoma (HCC) is one of the cancers with the highest morbidity and mortality. Sorafenib used to be the main treatment for unresectable HCC patients. However, regimens based on immune checkpoint inhibitors (ICIs) have attracted attention in recent years because of...
Main Authors: | Qing Lei, Xin Yan, Huimin Zou, Yixuan Jiang, Yunfeng Lai, Carolina Oi Lam Ung, Hao Hu |
---|---|
Format: | Article |
Language: | English |
Published: |
Springer
2022-09-01
|
Series: | Discover Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1007/s12672-022-00559-1 |
Similar Items
-
Efficacy and safety associated with immune checkpoint inhibitors in unresectable hepatocellular carcinoma: A re‐analysis of a meta‐analysis
by: Shouhao Zhou, et al.
Published: (2023-02-01) -
Clinical Outcomes Associated with Monotherapy and Combination Therapy of Immune Checkpoint Inhibitors as First-Line Treatment for Advanced Hepatocellular Carcinoma in Real-World Practice: A Systematic Literature Review and Meta-Analysis
by: Huimin Zou, et al.
Published: (2022-12-01) -
Efficacy and safety of combined targeted therapy and immunotherapy versus targeted monotherapy in unresectable hepatocellular carcinoma: a systematic review and meta-analysis
by: Teng-Kai Yang, et al.
Published: (2022-10-01) -
Downstaging Therapies for Unresectable Hepatocellular Carcinoma Prior to Hepatic Resection: A Systematic Review and Meta-Analysis
by: Xinyu Chen, et al.
Published: (2021-11-01) -
Immune Checkpoint Inhibitors Plus an Anti-VEGF Antibody as the First-Line Treatment for Unresectable Hepatocellular Carcinoma: A Network Meta-Analysis and Cost-Effectiveness Analysis
by: Lu Li, et al.
Published: (2022-06-01)