MCF7 Spheroid Development: New Insight about Spatio/Temporal Arrangements of TNTs, Amyloid Fibrils, Cell Connections, and Cellular Bridges

MCF7 Spheroid Development: New Insight about Spatio/Temporal Arrangements of TNTs, Amyloid Fibrils, Cell Connections, and Cellular Bridges

Human breast adenocarcinoma cells (MCF7) grow in three-dimensional culture as spheroids that represent the structural complexity of avascular tumors. Therefore, spheroids offer a powerful tool for studying cancer development, aggressiveness, and drug resistance. Notwithstanding the large amount of d...

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Bibliographic Details
Main Authors: Laura Pulze, Terenzio Congiu, Tiziana A. L. Brevini, Annalisa Grimaldi, Gianluca Tettamanti, Paola D’Antona, Nicolò Baranzini, Francesco Acquati, Federico Ferraro, Magda de Eguileor
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
MCF7 3D spheroid
TNTs
amyloid fibrils
gap junctions
cytoplasmic bridges
ROS scavenger
Online Access:https://www.mdpi.com/1422-0067/21/15/5400

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https://www.mdpi.com/1422-0067/21/15/5400

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