Immune system-related soluble mediators and COVID-19: basic mechanisms and clinical perspectives

Abstract During SARS-CoV-2 infection, an effective immune response provides the first line of defense; however, excessive inflammatory innate immunity and impaired adaptive immunity may harm tissues. Soluble immune mediators are involved in the dynamic interaction of ligands with membrane-bound rece...

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Main Authors: Mohammad Sadegh Soltani-Zangbar, Forough Parhizkar, Mojtaba Abdollahi, Navid Shomali, Leili Aghebati-Maleki, Sima Shahmohammadi Farid, Leila Roshangar, Ata Mahmoodpoor, Mehdi Yousefi
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-022-00948-7