Capturing Protein Domain Structure and Function Using Self-Supervision on Domain Architectures

Predicting biological properties of unseen proteins is shown to be improved by the use of protein sequence embeddings. However, these sequence embeddings have the caveat that biological metadata do not exist for each amino acid, in order to measure the quality of each unique learned embedding vector...

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Bibliographic Details
Main Authors: Damianos P. Melidis, Wolfgang Nejdl
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Algorithms
Subjects:
Online Access:https://www.mdpi.com/1999-4893/14/1/28