Lineage origin and transcriptional control of autoantigen-specific T-regulatory type 1 cells

Lineage origin and transcriptional control of autoantigen-specific T-regulatory type 1 cells

T Regulatory type-1 (TR1) cells represent an immunosuppressive T cell subset, discovered over 25 years ago, that produces high levels of interleukin-10 (IL-10) but, unlike its FoxP3+ T regulatory (Treg) cell counterpart, does not express FoxP3 or CD25. Experimental evidence generated over the last f...

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Bibliographic Details
Main Authors: Edgar Angelats, Pere Santamaria
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
autoimmunity
T-regulatory (Treg) cells
T-regulatory type 1 (TR1) cells
peptide-MHC
nanomedicine
T-follicular helper cells (Tfh)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1267697/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1267697/full

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