Serum IL-27 levels increase in subjects with hypothyroidism and are negatively correlated with the occurrence of nonalcoholic fatty liver disease

Serum IL-27 levels increase in subjects with hypothyroidism and are negatively correlated with the occurrence of nonalcoholic fatty liver disease

BackgroundThe level of serum interleukin-27 (IL-27) was significantly decreased in the obesity group. After injection of IL-27, obese mice showed significant weight loss,reduced fat accumulation, improved insulin resistance and hepatic steatosis.IL-27 plays a key role in the regulation of metabolic...

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Bibliographic Details
Main Authors: Yahui Wen, Heng Zhang, Ning Yang, Xia Gao, Zhe Chen, Jia Liu, Guang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Endocrinology
Subjects:
hypothyroidism
IL-27
NAFLD
dyslipidemia
lipid metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1173826/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1173826/full

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