Efficacy Validation of SARS-CoV-2-Inactivation and Viral Genome Stability in Saliva by a Guanidine Hydrochloride and Surfactant-Based Virus Lysis/Transport Buffer

Efficacy Validation of SARS-CoV-2-Inactivation and Viral Genome Stability in Saliva by a Guanidine Hydrochloride and Surfactant-Based Virus Lysis/Transport Buffer

To enhance biosafety and reliability in SARS-CoV-2 molecular diagnosis, virus lysis/transport buffers should inactivate the virus and preserve viral RNA under various conditions. Herein, we evaluated the SARS-CoV-2-inactivating activity of guanidine hydrochloride (GuHCl)- and surfactant (hexadecyltr...

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Bibliographic Details
Main Authors: James Gitau Komu, Dulamjav Jamsransuren, Sachiko Matsuda, Haruko Ogawa, Yohei Takeda
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
SARS-CoV-2-inactivation
virus lysis/transport buffer
RNA stability
saliva
guanidine hydrochloride
Online Access:https://www.mdpi.com/1999-4915/15/2/509

Internet

https://www.mdpi.com/1999-4915/15/2/509

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