Interictal dysfunction of a brainstem descending modulatory center in migraine patients.

The brainstem contains descending circuitry that can modulate nociceptive processing (neural signals associated with pain) in the dorsal horn of the spinal cord and the medullary dorsal horn. In migraineurs, abnormal brainstem function during attacks suggest that dysfunction of descending modulation...

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Bibliographic Details
Main Authors: Eric A Moulton, Rami Burstein, Shannon Tully, Richard Hargreaves, Lino Becerra, David Borsook
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2582961?pdf=render