Interictal dysfunction of a brainstem descending modulatory center in migraine patients.
The brainstem contains descending circuitry that can modulate nociceptive processing (neural signals associated with pain) in the dorsal horn of the spinal cord and the medullary dorsal horn. In migraineurs, abnormal brainstem function during attacks suggest that dysfunction of descending modulation...
Main Authors: | Eric A Moulton, Rami Burstein, Shannon Tully, Richard Hargreaves, Lino Becerra, David Borsook |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2582961?pdf=render |
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