Causal relationship between atrial fibrillation and leukocyte telomere length: A two sample, bidirectional Mendelian randomization study

Causal relationship between atrial fibrillation and leukocyte telomere length: A two sample, bidirectional Mendelian randomization study

BackgroundAtrial fibrillation (AF) is an age-related disease, while telomeres play a central role in aging. But the relationship between AF and telomere length (LTL) is still controversial. This study aims to examine the potential causal association between AF and LTL by using Mendelian randomizatio...

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Bibliographic Details
Main Authors: Zimo Sha, Tianzhichao Hou, Taojie Zhou, Yang Dai, Yangyang Bao, Qi Jin, Jing Ye, Yiming Lu, Liqun Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
bidirectional Mendelian randomization (MR)
atrial fibrillation
genome-wide association study
leukocyte telomere length
expression quantitative trait loci (eQTL)
protein quantitative trait loci (pQTL)
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1093255/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1093255/full

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