The Interplay between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation

The Interplay between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation

Finasteride (Fin) causes androgen imbalance by inhibiting the conversion of testosterone (T) to its more active metabolite, dihydrotestosterone (DHT). Androgen receptors (AR) are present (e.g., in hepatocytes), which have well-developed endoplasmic reticulum (ERet). Cellular protein quality control...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Sylwia Rzeszotek, Agnieszka Kolasa, Anna Pilutin, Kamila Misiakiewicz-Has, Katarzyna Sielatycka, Barbara Wiszniewska
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	MDPI AG 2022-10-01
Cyfres:	Biomedicines
Pynciau:	finasteride androgen imbalance androgen receptor endoplasmic reticulum stress oxidative stress liver
Mynediad Ar-lein:	https://www.mdpi.com/2227-9059/10/11/2725

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