Coexistence of trisomy 12 and del(13)(q14.3) in two patients with chronic lymphocytic leukemia

Coexistence of trisomy 12 and del(13)(q14.3) in two patients with chronic lymphocytic leukemia

We describe two patients with diagnosis of chronic lymphocytic leukemia (CLL) in whom interphase fluo­rescence in situ hybridization (FISH) analysis revealed trisomy 12 and del(13)(q14.3) occurring in the same clone. These abnormalities are rarely seen together and the prognostic relevance of their...

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Bibliographic Details
Main Authors: Denčić-Fekete Marija, Antić D., Davidović-Mrsić Sanja, Franić Ivana, Kraguljac-Kurtović Nada, Bila Jelena, Elezović I.
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2009-01-01
Series:Archives of Biological Sciences
Subjects:
Chronic lymphocytic leukemia
trisomy 12,13q deletion
chromosomal abnormalities
FISH
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2009/0354-46640904607D.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0354-4664/2009/0354-46640904607D.pdf

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