Gingival-derived mesenchymal stem cell therapy regenerated the radiated salivary glands: functional and histological evidence in murine model

Gingival-derived mesenchymal stem cell therapy regenerated the radiated salivary glands: functional and histological evidence in murine model

Abstract Background Radiotherapy in head and neck cancer management causes degeneration of the salivary glands (SG). This study was designed to determine the potential of gingival mesenchymal stem cells (GMSCs) as a cell-based therapy to regenerate irradiated parotid SG tissues and restore their fun...

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Bibliographic Details
Main Authors: Hagar M. Zayed, Nevine H. Kheir El Din, Ashraf M. Abu-Seida, Asmaa A. Abo Zeid, Ola M. Ezzatt
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Stem Cell Research & Therapy
Subjects:
Apop-Tag Peroxidase
Anti-proliferating cell nuclear antigen
Oral derived stem cells
Guinea pigs
Xerostomia
Online Access:https://doi.org/10.1186/s13287-024-03659-7

Internet

https://doi.org/10.1186/s13287-024-03659-7

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