CLDN6 inhibits breast cancer metastasis through WIP-dependent actin cytoskeleton-mediated autophagy

CLDN6 inhibits breast cancer metastasis through WIP-dependent actin cytoskeleton-mediated autophagy

Abstract Background As a breast cancer suppressor gene, CLDN6 overexpression was found to inhibit breast cancer metastasis in our previous studies, but the specific mechanism remains unclear. This study aimed to clarify the role and mechanism of CLDN6 in inhibiting breast cancer metastasis. Methods...

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Bibliographic Details
Main Authors: Yuan Dong, Qiu Jin, Minghao Sun, Da Qi, Huinan Qu, Xinqi Wang, Chengshi Quan
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
CLDN6
Breast cancer
Metastasis
Autophagy
WIP
Actin cytoskeleton
Online Access:https://doi.org/10.1186/s13046-023-02644-x

Internet

https://doi.org/10.1186/s13046-023-02644-x

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