Sleep, Sirtuin 1 and Alzheimer’s disease: A review

Sleep plays a major role in brain health, and cognition. Disrupted sleep is a well-described symptom of Alzheimer’s disease (AD). However, accumulating evidence suggests suboptimal sleep also increases AD risk. The deacetylase Sirtuin 1 (Sirt 1), encoded by the SIRT1 gene, impacts sleep via its rela...

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Bibliographic Details
Main Authors: Mehrane Mehramiz, Tenielle Porter, Simon M. Laws, Stephanie R. Rainey-Smith
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Aging Brain
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589958922000226